%0 Thesis %A YONG, MICHELLE KAREN %D 2018 %T The use of a novel IFN-γ release assay to characterise cytomegalovirus (CMV) and immunological outcomes in transplant and HIV-infected individuals %U https://bridges.monash.edu/articles/thesis/The_use_of_a_novel_IFN-_release_assay_to_characterise_cytomegalovirus_CMV_and_immunological_outcomes_in_transplant_and_HIV-infected_individuals/6264626 %R 10.4225/03/5af925cabfa10 %K Infectious Diseases %K Infectious Diseases %X A lowered immune system in the setting of stem cell transplantation or human immunodeficiency virus (HIV) infection places individuals at high risk of infectious and non-infectious complications. This research evaluated the clinical use of easy, rapid, high throughput immune biomarkers to predict clinical outcomes such as cytomegalovirus (CMV)-related morbidity, end organ disease and/or overall mortality. The studies in this thesis showed that these markers were able to predict infectious complications and/or death. Use of these markers will have an important impact in the health care of future individuals undergoing immunosuppression. %I Monash University