10.4225/03/5b1f66dca117b SHAKYALAL VIDHURA FERNANDO SHAKYALAL VIDHURA FERNANDO Melatonin in Assisted Reproductive Technology - The MIART Trial Monash University 2019 Melatonin Assisted Reproductive Technology IVF ART in-vitro fertilisation Sleep Obstetrics and Gynaecology Reproduction 2019-03-20 23:59:58 Thesis https://bridges.monash.edu/articles/thesis/Melatonin_in_Assisted_Reproductive_Technology_-_The_MIART_Trial/6489344 Oxygen free radicals are created during the IVF process. These have the potential to damage DNA in human eggs and embryos thereby reducing pregnancy rates after IVF. Melatonin has the ability to reduce the effects of oxygen free radicals. In the Melatonin in Assisted Reproductive Technology trial, I found that, while oral melatonin can increase levels of melatonin in follicular fluid, this does not significantly improve IVF success rates.