10.26180/5b72277427700
ASHLEE JADE CONWAY
ASHLEE JADE
CONWAY
The Investigation of Red Cell Mutants Identified in an ENU Mutagenesis Screen
Monash University
2019
Haematology
Erythropoiesis
Mouse models
Mutagenesis
Haematology
2019-03-14 04:05:03
Thesis
https://bridges.monash.edu/articles/thesis/The_Investigation_of_Red_Cell_Mutants_Identified_in_an_ENU_Mutagenesis_Screen/6962855
This thesis describes the study of mutant mice which harbour congenital defects in various aspects of erythropoiesis, obtained through ENU mutagenesis. Mice were phenotyped and characterised in order to understand the underlying genetic and molecular mechanisms which resulted in their red cell defects, as well as their clinical relevance to human red cell diseases.