10.26180/5c5a4d4251bc5
SUPREET KAUR
SUPREET
KAUR
Role of Hepatic ROS in the Development of Obesity, Steatosis and NAFLD.
Monash University
2019
ROS
NAFLD
NASH
HCC
Steatosis
NOX4
GPX1
Biochemistry
2019-02-06 02:58:08
Thesis
https://bridges.monash.edu/articles/thesis/Role_of_Hepatic_ROS_in_the_Development_of_Obesity_Steatosis_and_NAFLD_/7676204
Metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD), involve excess generation of reactive oxygen species (ROS). An imbalance in ROS generation and elimination has been linked to the development of NAFLD, but the precise mechanisms are not clear. This body of research redefines the role of ROS in the pathogenesis of NAFLD and demonstrates a protective role for ROS in NAFLD pathogenesis.