10.26180/5c5a4d4251bc5 SUPREET KAUR SUPREET KAUR Role of Hepatic ROS in the Development of Obesity, Steatosis and NAFLD. Monash University 2019 ROS NAFLD NASH HCC Steatosis NOX4 GPX1 Biochemistry 2019-02-06 02:58:08 Thesis https://bridges.monash.edu/articles/thesis/Role_of_Hepatic_ROS_in_the_Development_of_Obesity_Steatosis_and_NAFLD_/7676204 Metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD), involve excess generation of reactive oxygen species (ROS). An imbalance in ROS generation and elimination has been linked to the development of NAFLD, but the precise mechanisms are not clear. This body of research redefines the role of ROS in the pathogenesis of NAFLD and demonstrates a protective role for ROS in NAFLD pathogenesis.