10.26180/5cfefd01034d6 EILEEN GRACE MERRIMAN EILEEN GRACE MERRIMAN Isolated Distal Vein Deep Vein Thrombosis: Diagnosis and Management Strategies Monash University 2019 Distal vein DVT IDDVT Medicine 2019-06-11 00:59:43 Thesis https://bridges.monash.edu/articles/thesis/Isolated_Distal_Vein_Deep_Vein_Thrombosis_Diagnosis_and_Management_Strategies/8251538 This multicentre prospective cohort study enrolled patients with isolated distal deep vein DVT in Australia and New Zealand. 140 (70%) were assigned to two weeks anticoagulation (asymptomatic; group C); 56 (28%) to group B (ongoing symptoms; 6 weeks anticoagulation); and three patients (2%) had proximal extension on 2-week ultrasound (group A). Two patients in the two-week anticoagulation arm had symptomatic distal DVT recurrence; VTE recurrence rate 3/131; 2.3% (95% CI 0.47-6.55%). There were no symptomatic proximal DVT/PE recurrences, no major bleeding episodes, and a low rate of mild PTS (4.3%, 95% CI 1.7-8.6%), with no episodes of severe PTS.