Outcomes in Non-Small Cell Lung Cancer: modelling survival and thromboembolism risk prediction

2018-07-13T01:42:23Z (GMT) by MARLIESE RENEE ALEXANDER
This thesis aimed to undertake research to facilitate or drive initiatives to improve outcomes for patients with lung cancer – the most common and deadly cancer in Australia and globally. Specific objectives were to develop overall survival (OS) and thromboembolism (TE) risk prediction models for patients diagnosed with non-small cell lung cancer (NSCLC). The thesis is presented in two parts. Part one reports outcomes analyses from a cohort of Victorian patients diagnosed with lung cancer between 2012 and 2014. Part two investigates thrombogenic biomarkers for TE prediction and includes a single centre prospective observational cohort study conducted between 2014 and 2017.