Monash University
Browse

Embargoed and Restricted Access

Reason: Under embargo until July 2018. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Synthesis and characterisation of new platinum complexes with potential anti-cancer properties

thesis
posted on 2017-01-24, 00:16 authored by Luu, Jenny
This thesis focuses on developing new platinum complexes with potential anti-cancer properties. The research is based around the platinum based drug cisplatin which is a successful chemotherapy agent currently being used for various cancer treatments. In particular it is mainly used against testicular cancer with a cure rate of at least 90%. However, despite its success there are still limitations such as the issue of resistances and side effects. This research extends a number of new synthetic methods to organoplatinum(II) complexes which have the potential to overcome these issues. The complexes prepared have been tested for anti-cancer activity against the appropriate cell lines.

History

Campus location

Australia

Principal supervisor

Deacon Glen

Year of Award

2015

Department, School or Centre

Chemistry

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Science

Usage metrics

    Faculty of Science Theses

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC